Features of the functional state of the fetoplacental complex in pregnant women with a history of sexually transmitted infections

The objective: a study of the features for formation and functioning fetoplacental complex in pregnant women with history sexually transmitted infections.Materials methods. We examined 50 infections (I group – main group). control consisted 30 without somatic gynecological pathology, who had vaginal delivery. All underwent comprehensive clinical examination, taking into account complaints, medical history, objective additional methods examination. levels estriol, cortisol, placental lactogen progesterone blood serum state terms 18–20th, 28–30th 38–40th weeks were determined.Results. In I group, starting from 18th there was significant decrease secretion (160,8±15,9 nmol/L versus 202,4±5,5 nmol/L, respectively; p<0,05), (77,5±13,2 91,3±23,8 nmol/L)/ This means that already these stages pregnancy are signs dysfunction infections. changes functional at more pronounced, as evidenced by an increase frequency early intrauterine growth restriction (12.0 %), disorders fetal breathing (11.0 %) movements (18.0 (according to biophysical profile score assessment); premature placenta, increased hormonal insufficiency first hemodynamic (an flow umbilical artery uterine arteries slight circulation middle cerebral fetus). At final assessment condition infections, satisfactory observed 24 % cases, compensated ultrasound occurred 46.0 cases; subcompensated 20.0 decompensated 10.0 respectively, which causes high obstetric perinatal complications this women.Conclusions. is characterized level fetus, placenta amount amniotic fluid on background pronounced endocrinological disorders, requires prevention pre-pregnancy period.